Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096472 | 0.94 | GAA (0.33) | GAAHSD17B3OPRM1OPRD1OPRK1 | |
| SCHEMBL4488779 | 0.77 | — | — | |
| SCHEMBL25340168 | 0.74 | GAA (0.41) | GAA | |
| SCHEMBL18670682 | 0.74 | GAA (0.41) | GAA | |
| SCHEMBL4426595 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL13740080 | 0.73 | PTPN7 (0.33) | — | |
| SCHEMBL3716884 | 0.70 | ESR2 (0.31) | — | |
| SCHEMBL28435520 | 0.69 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4437885 | 0.69 | — | — | |
| SCHEMBL21295576 | 0.69 | GAA (0.37) | GAAHSD17B3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809626-A2 | ARYL SUBSTITUTED 8-AZABICYCLO[3.2.1]OCTANE COMPOUNDS AS LIGANDS OF THE MELANIN CONCENTRATING HORMONE RECEPTOR | Neurogen Corporation (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006044174-A9 | ARYL SUBSTITUTED 8-AZABICYCLO[3.2.1]OCTANE COMPOUNDS AS LIGANDS OF THE MELANIN CONCENTRATING HORMONE RECEPTOR | NEUROGEN CORP (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006044174-A2 | ARYL SUBSTITUTED 8-AZABICYCLO[3.2.1]OCTANE COMPOUNDS AS LIGANDS OF THE MELANIN CONCENTRATING HORMONE RECEPTOR | NEUROGEN CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |