Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210189 | 0.86 | HRH3 (0.50) | HRH3USP2KDM4EALDH1A1MAPT | |
| SCHEMBL20579629 | 0.84 | OPRD1 (0.43) | HRH3USP2KDM4EALDH1A1MAPT | |
| SCHEMBL5211181 | 0.82 | HRH3 (0.53) | HRH3 | |
| SCHEMBL5210077 | 0.82 | HRH3 (0.58) | HRH3 | |
| SCHEMBL5212236 | 0.82 | HRH3 (0.76) | HRH3 | |
| SCHEMBL5208401 | 0.81 | HRH3 (0.58) | HRH3 | |
| SCHEMBL5209775 | 0.81 | HRH3 (0.53) | HRH3USP2 | |
| SCHEMBL5214338 | 0.81 | HRH3 (0.57) | HRH3ALDH1A1 | |
| SCHEMBL5210399 | 0.80 | HRH3 (0.62) | HRH3KDM4EALDH1A1MAPT | |
| SCHEMBL10184117 | 0.76 | ACACB (0.46) | HRH3USP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |