Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.61 |
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212777 | 1.00 | CNR2 (0.61) | CNR2KDM5AIRAK4EGFRBTK | |
| SCHEMBL5212774 | 1.00 | CNR2 (0.61) | CNR2KDM5AIRAK4EGFRBTK | |
| SCHEMBL5215693 | 0.84 | CNR2 (0.59) | CNR2IRAK4 | |
| SCHEMBL5215525 | 0.82 | CNR2 (0.63) | CNR2 | |
| SCHEMBL5213329 | 0.82 | CNR2 (0.62) | CNR2 | |
| SCHEMBL5212172 | 0.81 | CNR2 (0.68) | CNR2 | |
| SCHEMBL4648469 | 0.80 | CNR2 (0.87) | CNR2 | |
| SCHEMBL5214047 | 0.79 | CNR2 (0.58) | CNR2 | |
| SCHEMBL5077114 | 0.78 | CNR2 (0.84) | CNR2 | |
| SCHEMBL3379002 | 0.78 | CNR2 (0.58) | CNR2EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | claimed |
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | disclosed |