Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188445 | 0.87 | KMT2A (0.46) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL25220513 | 0.82 | ALDH1A1 (0.47) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL1903391 | 0.77 | GRM5 (0.65) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL4688294 | 0.76 | NPSR1 (0.51) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL188791 | 0.75 | AKR1C3 (0.60) | KMT2AMEN1MAPTLMNAAKR1C3 | |
| SCHEMBL1901740 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1MAPTTSHRNPC1 | |
| SCHEMBL188725 | 0.73 | ALDH1A1 (0.44) | MAPTLMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1899800 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL1899796 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL188675 | 0.71 | MAPT (0.47) | KMT2AMEN1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101353313-A | Process to produce oxazolidinones | UPJOHN CO (US) | 2009-01-28 | — | — | CN | claimed |
| EP-1028940-B1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-04-18 | — | — | EP | claimed |
| CN-1275122-A | Process for preparing oxazolidinones | UPJOHN CO (US) | 2000-11-29 | — | — | CN | claimed |