SCHEMBL5214161

SCHEMBL5214161

CN(C)C(=O)CCCc1ccc(N2CCOCC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.49
SLC13A5 Q86YT5 1/20 0.48
GAA P10253 1/20 0.45
AOC3 Q16853 1/20 0.45
GSK3B P49841 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALOX5 P09917 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
S1PR1 P21453 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29639812 0.82 MAPT (0.52) MAPTSLC13A5GSK3BL3MBTL1THRA
SCHEMBL7618937 0.81 MAPT (0.52) MAPTSLC13A5AOC3GSK3BL3MBTL1
SCHEMBL22500352 0.78 MAPT (0.51) MAPTSLC13A5GSK3BL3MBTL1THRA
SCHEMBL2330058 0.78 MAPT (0.57) MAPTSLC13A5GAAGSK3BL3MBTL1
SCHEMBL27989630 0.77 MAPT (0.59) MAPTSLC13A5GAAGSK3BL3MBTL1
SCHEMBL7530628 0.76 LMNA (0.62) MAPTSLC13A5GAAGSK3BL3MBTL1
SCHEMBL28927706 0.76 GSK3B (0.60) MAPTSLC13A5GSK3BL3MBTL1THRA
SCHEMBL3399680 0.76 LMNA (0.52) MAPTSLC13A5GAAL3MBTL1THRA
SCHEMBL22558673 0.76 SLC13A5 (0.50) MAPTSLC13A5GAAGSK3BL3MBTL1
SCHEMBL28299497 0.75 MAPT (0.55) MAPTSLC13A5GAAGSK3BL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1779150-A2 LAMINATED OPTICAL ARTICLE 3M Innovative Properties Company (US) 2007-05-02 EP disclosed
WO-2006019666-A2 LAMINATED OPTICAL ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-02-23 WO disclosed
EP-1435020-A2 AQUEOUS DEVELOPABLE PHOTOIMAGEABLE THICK FILM COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-07-07 EP disclosed
WO-2003032087-A2 AQUEOUS DEVELOPABLE PHOTOIMAGEABLE THICK FILM COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-04-17 WO disclosed