Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 1.00 |
| ▸ | PTGER2 | P43116 | 7/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 6/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183543 | 1.00 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2446235 | 1.00 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2446214 | 1.00 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214584 | 0.97 | PTGER4 (0.94) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214409 | 0.97 | PTGER4 (0.94) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214403 | 0.97 | PTGER4 (0.94) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5217330 | 0.95 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214140 | 0.95 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5217323 | 0.95 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL14464335 | 0.91 | PTGER4 (0.84) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113388-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-05-06 | — | — | US | claimed |
| US-20090042885-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-02-12 | — | — | US | claimed |
| US-20080234337-A1 | Preventive and/or Remedy for Hyperkalemia Containing Ep4 Agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-25 | — | — | US | claimed |
| US-20080021021-A1 | Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | US | claimed |
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | claimed |
| EP-1782829-A1 | PREVENTIVE AND/OR REMEDY FOR HYPERKALEMIA CONTAINING EP4 AGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-09 | — | — | EP | claimed |
| US-20050124577-A1 | 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | claimed |
| US-6849657-B2 | 2-pyrrolidone derivatives as prostanoid agonists | SYNTEX (U.S.A.) LLC (US) | 2005-02-01 | — | — | US | claimed |
| EP-1481976-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-01 | — | — | EP | claimed |
| US-20030064964-A1 | 2-pyrrolidone derivatives as prostanoid agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-03 | — | — | US | claimed |
| US-8026273-B2 | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-27 | — | — | US | disclosed |
| US-7858610-B2 | Preventive and/or remedy for lower urinary tract diseases containing EP4 agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20100291230-A1 | Novel Pesticide Compositions | BROMINE COMPOUNDS LTD. (IL) | 2010-11-18 | — | — | US | disclosed |
| US-20100113388-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-7683094-B2 | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |
| EP-0026034-A1 | 5-Amino-4-cyano-1-(2,4,6-trichlorophenyl)pyrazole, process for its preparation, herbicidal compositions containing it and their use | FBC LIMITED (GB) | 1981-04-01 | — | — | EP | disclosed |
| US-4053480-A | 1-THIADIAZOLYL-5-PHENOXY- AND PHENYLTHIOALKANOYLOXY IMIDAZOLIDINONES | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-3978107-A | NOVEL CYCLOHEXYL CARBAMATES AND HERBICIDAL AND ACARICIDAL COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
| US-3953507-A | N-t-butyl-α-(3,5-substituted phenoxy) alkyl amides and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124577-A1 | 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | PTGER2, PTGIS, HPGDS | PTGER4 16/4885PTGER2 1/4885PTGER3 12/4885 |
| US-20090042885-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | PTGER2, PTGIS, HPGDS | PTGER4 19/4885PTGER2 1/4885PTGER3 16/4885 |
| US-20030064964-A1 | 2-pyrrolidone derivatives as prostanoid agonists | PTGER1, PTGER4, PTGIR | PTGER4 2/4885PTGER2 4/4885PTGER3 7/4885 |
| US-20080234337-A1 | Preventive and/or Remedy for Hyperkalemia Containing Ep4 Agonist | KCNJ4, KCNK4, KCNA4 | PTGER4 86/4885PTGER2 333/4885PTGER3 297/4885 |
| US-20100291230-A1 | Novel Pesticide Compositions | ACHE, PTMS, CNP | PTGER4 2927/4885PTGER2 3516/4885PTGER3 2911/4885 |
| US-20080021021-A1 | Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist | PTGER4, PTGES3, CYSLTR1 | PTGER4 1/4885PTGER2 13/4885PTGER3 4/4885 |
| US-20100113388-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | PTGER2, PTGIS, HPGDS | PTGER4 19/4885PTGER2 1/4885PTGER3 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.