Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 9/20 | 0.49 |
| ▸ | NOS2 | P35228 | 9/20 | 0.49 |
| ▸ | NOS3 | P29474 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295542 | 0.98 | NOS1 (0.50) | CYP1A2NOS1NOS2NOS3DPP4 | |
| SCHEMBL1168660 | 0.92 | NOS1 (0.44) | CYP1A2NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL6510677 | 0.91 | — | — | |
| SCHEMBL7636658 | 0.90 | NOS1 (0.43) | CYP1A2NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL2106032 | 0.90 | NOS1 (0.43) | CYP1A2NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL4857180 | 0.87 | NOS1 (0.48) | CYP1A2NOS1NOS2NOS3 | |
| SCHEMBL1691768 | 0.85 | NOS1 (0.42) | CYP1A2NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL1219807 | 0.85 | — | — | |
| SCHEMBL10707537 | 0.83 | EPHX1 (0.41) | CYP1A2NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL7634559 | 0.83 | EPHX1 (0.41) | CYP1A2NOS1NOS2NOS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765798-A2 | 1,2,4- THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| WO-2005037805-A2 | 1,2,4-THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | CYP4F3, CYP4B1, CYP4X1 | CYP1A2 39/4885NOS1 1180/4885NOS2 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.