SCHEMBL5215319

SCHEMBL5215319

COCC(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27993076 1.00
SCHEMBL27676472 1.00
SCHEMBL13327227 0.83
SCHEMBL18330740 0.75
SCHEMBL1627599 0.73 TP53 (0.42)
SCHEMBL8609348 0.73
SCHEMBL9119881 0.73
SCHEMBL27993283 0.73
SCHEMBL2801171 0.73
SCHEMBL27993077 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104230987-B A kind of [1-halo-(2-propoxyl group)]-methylphosphonic acid compounds and preparation thereof and application 上海科生物医药有限公司 2016-09-21 CN disclosed
US-9303059-B2 Chemoselective enrichment for compound isolation INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2016-04-05 US disclosed
US-9303059-B2 Chemoselective enrichment for compound isolation INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2016-04-05 US disclosed
US-9079983-B2 Chemoselective enrichment for compound isolation INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-07-14 US disclosed
US-9079983-B2 Chemoselective enrichment for compound isolation INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-07-14 US disclosed
CN-104230987-A [1-halo-(2-propoxy)]-methylphosphoric acid compounds as well as preparation and application thereof SHANGHAI KEYI BIOLOG MEDICINE CO LTD 2014-12-24 CN disclosed
US-20140107328-A1 CHEMOSELECTIVE ENRICHMENT FOR COMPOUND ISOLATION INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION 2014-04-17 US disclosed
US-20140107328-A1 CHEMOSELECTIVE ENRICHMENT FOR COMPOUND ISOLATION INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION 2014-04-17 US disclosed
CN-1827627-B Novel acyclic nucleoside phosphonic acid and its ester derivatives and pharmaceutical use thereof BEIJING MEIBEITA PHARMACEUTICAL RES CO LTD 2011-05-11 CN disclosed
EP-1198456-B1 POTASSIUM CHANNEL OPENERS ABBOTT LAB (US) 2007-09-19 EP disclosed
US-20020147230-A1 Aminal Diones as potassium channel openers ABBOTT LABORATORIES 2002-10-10 US disclosed
WO-2002062762-A2 POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2002-08-15 WO disclosed
WO-2002062761-A1 AMINAL DIONES AS POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2002-08-15 WO disclosed
EP-1198456-A2 POTASSIUM CHANNEL OPENERS Abbott Laboratories (US) 2002-04-24 EP disclosed
US-20020028836-A1 Potassium channel openers ABBVIE INC. 2002-03-07 US disclosed
WO-2001009096-A2 POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2001-02-08 WO disclosed
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP disclosed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US disclosed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US disclosed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP disclosed