⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327227 | 0.83 | — | — | |
| SCHEMBL15509468 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL5215319 | 0.75 | — | — | |
| SCHEMBL27676472 | 0.75 | — | — | |
| SCHEMBL27993076 | 0.75 | — | — | |
| SCHEMBL1228508 | 0.73 | — | — | |
| SCHEMBL8609348 | 0.73 | — | — | |
| SCHEMBL14141390 | 0.73 | — | — | |
| SCHEMBL2801171 | 0.73 | — | — | |
| SCHEMBL27993283 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786164-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | Ting Therapeutics LLC (US) | 2021-03-03 | — | — | EP | disclosed |
| US-20180161340-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2018-06-14 | — | — | US | disclosed |
| WO-2016205806-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2016-12-22 | — | — | WO | disclosed |