Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 9/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014969 | 0.98 | CYP1A2 (0.56) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL24489452 | 0.98 | CYP1A2 (0.54) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL23014863 | 0.96 | CYP1A2 (0.52) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL23014934 | 0.91 | CYP1A2 (0.46) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL23815628 | 0.91 | CYP1A2 (0.56) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL9512914 | 0.88 | CYP1A2 (0.45) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL75092 | 0.86 | CYP1A2 (0.50) | CYP1A2SIGMAR1NAAAEPHX1KDM4E | |
| SCHEMBL18902841 | 0.86 | CYP1A2 (0.39) | CYP1A2SIGMAR1NAAA | |
| SCHEMBL23014799 | 0.86 | CYP1A2 (0.39) | CYP1A2SIGMAR1NAAA | |
| SCHEMBL14740174 | 0.86 | SIGMAR1 (0.56) | CYP1A2SIGMAR1NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |