Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965673 | 0.83 | CRHR1 (0.60) | CRHR1CRHR2SMPD3 | |
| SCHEMBL5209540 | 0.81 | CRHR1 (0.48) | CRHR1CRHR2 | |
| SCHEMBL5209535 | 0.81 | CRHR1 (0.50) | CRHR1CRHR2 | |
| SCHEMBL5213703 | 0.79 | CRHR1 (0.43) | CRHR1CRHR2 | |
| SCHEMBL3964552 | 0.78 | CRHR1 (0.56) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3965066 | 0.78 | CRHR1 (0.56) | CRHR1CRHR2SMPD3 | |
| SCHEMBL13614761 | 0.78 | CRHR1 (0.59) | CRHR1CRHR2 | |
| SCHEMBL3970535 | 0.77 | CRHR1 (0.55) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3920973 | 0.77 | CRHR1 (0.61) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3927749 | 0.76 | CRHR1 (0.60) | CRHR1CRHR2SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869049-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006102194-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | WO | disclosed |