Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 15/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215084 | 1.00 | AVPR1A (0.48) | AVPR1AALDH1A1LMNAACHEHTR1A | |
| SCHEMBL5214278 | 0.90 | AVPR1A (0.47) | AVPR1AACHEHTR1A | |
| SCHEMBL5214267 | 0.90 | AVPR1A (0.47) | AVPR1AACHEHTR1A | |
| SCHEMBL5214155 | 0.85 | AVPR1A (0.49) | AVPR1ALMNAACHEHTR1A | |
| SCHEMBL5215700 | 0.76 | AVPR1A (0.78) | AVPR1AALDH1A1 | |
| SCHEMBL5215932 | 0.74 | AVPR1A (0.65) | AVPR1A | |
| SCHEMBL5005694 | 0.73 | AVPR1A (0.60) | AVPR1A | |
| SCHEMBL5215088 | 0.72 | AVPR1A (0.60) | AVPR1AACHE | |
| SCHEMBL5212381 | 0.71 | HTR1A (0.40) | AVPR1AALDH1A1LMNAACHEHTR1A | |
| SCHEMBL5212390 | 0.71 | HTR1A (0.40) | AVPR1AALDH1A1LMNAACHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558598-B1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LTD (GB) | 2007-07-18 | — | — | EP | claimed |