Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019025 | 0.87 | LOXL2 (0.72) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL10336939 | 0.86 | PDPK1 (0.68) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL16169666 | 0.82 | LOXL2 (0.46) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL15805860 | 0.82 | LOXL2 (0.46) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL3969950 | 0.82 | LOXL2 (0.73) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL18313516 | 0.81 | PDPK1 (0.59) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL9454664 | 0.81 | PDPK1 (0.59) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL12747050 | 0.81 | PDPK1 (0.59) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL18586399 | 0.81 | PDPK1 (0.59) | LOXL2PDPK1FFAR1CARM1PRMT1 | |
| SCHEMBL5012764 | 0.80 | FFAR1 (0.56) | LOXL2PDPK1FFAR1CARM1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581516-A4 | 3-HETEROCYCLIC BENZYLAMIDE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | BRISTOL MYERS SQUIBB CO (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1581516-A2 | 3-HETEROCYCLIC BENZYLAMIDE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | Bristol-Myers Squibb Company (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004047744-A2 | 3-HETEROCYCLIC BENZYLAMIDE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-10 | — | — | WO | disclosed |