SCHEMBL5216635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5213071	0.93	PTK2 (0.41)	PTK2PTK2BJAK2STAT6AURKA
	SCHEMBL5208214	0.89	PTK2 (0.61)	PTK2PTK2BAURKABRD4
	SCHEMBL5212938	0.88	PTK2 (0.61)	PTK2PTK2BAURKABRD4
	SCHEMBL5213023	0.85	PTK2 (0.63)	PTK2PTK2BJAK2NTRK1TYK2
	SCHEMBL5212767	0.85	ULK1 (0.47)	PTK2PTK2BJAK2CDK2
	SCHEMBL5213817	0.84	CDK1 (0.47)	PTK2BJAK2AURKA
	SCHEMBL5213474	0.84	PTK2 (0.61)	PTK2PTK2B
	SCHEMBL6211231	0.83	CDK1 (0.43)	PTK2PTK2BJAK2NTRK1STAT6
	SCHEMBL5212591	0.83	PTK2 (0.51)	PTK2PTK2B
	SCHEMBL6240449	0.82	CDK1 (0.43)	PTK2PTK2BSTAT6CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.