Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 14/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217039 | 1.00 | PPARA (0.46) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL5215875 | 0.85 | PPARD (0.63) | PPARAPPARGPPARD | |
| SCHEMBL5218962 | 0.85 | PPARD (0.63) | PPARAPPARGPPARD | |
| SCHEMBL5221374 | 0.85 | PPARD (0.63) | PPARAPPARGPPARD | |
| SCHEMBL5217052 | 0.81 | PPARD (0.52) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL4468965 | 0.77 | PPARD (0.53) | PPARAPPARGPPARDTP53MAPT | |
| SCHEMBL5850797 | 0.76 | PPARD (0.45) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL5218580 | 0.75 | PPARA (0.61) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL5219166 | 0.75 | PPARD (0.54) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL14432285 | 0.75 | PPARD (0.54) | PPARAPPARGRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2007-08-15 | — | — | EP | disclosed |