Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.52 |
| ▸ | PPARA | Q07869 | 12/20 | 0.52 |
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218966 | 0.86 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL5217039 | 0.81 | PPARA (0.46) | PPARDPPARAPPARGRXRARXRB | |
| SCHEMBL5217047 | 0.81 | PPARA (0.46) | PPARDPPARAPPARGRXRARXRB | |
| SCHEMBL4680724 | 0.77 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL6224733 | 0.77 | PPARD (0.52) | PPARDPPARAPPARGMAPT | |
| SCHEMBL6613722 | 0.77 | PPARG (0.74) | PPARDPPARAPPARG | |
| SCHEMBL4676727 | 0.74 | PPARG (0.67) | PPARDPPARAPPARG | |
| SCHEMBL6219486 | 0.73 | PPARA (0.47) | PPARDPPARAPPARG | |
| SCHEMBL4475618 | 0.73 | PPARD (0.45) | PPARDPPARAPPARGMAPT | |
| SCHEMBL6616535 | 0.73 | PPARD (0.71) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2007-08-15 | — | — | EP | disclosed |