Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.35 |
| ▸ | BID | P55957 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114499 | 0.93 | PARK7 (0.40) | PARK7MCL1BCL2A1CA1CA4 | |
| SCHEMBL5110054 | 0.93 | PARK7 (0.40) | PARK7MCL1BCL2A1CA1CA4 | |
| SCHEMBL5111211 | 0.88 | PARK7 (0.48) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL5111207 | 0.88 | PARK7 (0.48) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL5114732 | 0.85 | PARK7 (0.44) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL5114729 | 0.85 | PARK7 (0.44) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL14287339 | 0.85 | PARK7 (0.44) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL5110704 | 0.85 | PARK7 (0.44) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL5110708 | 0.85 | PARK7 (0.44) | PARK7MCL1BCL2A1CA12CA1 | |
| SCHEMBL14287374 | 0.85 | PARK7 (0.41) | PARK7MCL1BCL2A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828124-A1 | BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development (FR) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063863-A1 | BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-06-22 | — | — | WO | disclosed |