Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223122 | 0.99 | CETP (0.38) | CETPMMECTSLCTSBCTSK | |
| SCHEMBL5223128 | 0.77 | CETP (0.38) | CETPMMECTSLCTSBCTSK | |
| SCHEMBL5390344 | 0.76 | CSNK1E (0.51) | CETPMME | |
| SCHEMBL4688261 | 0.75 | CSNK1E (0.50) | CETPMME | |
| Hydrochloric Acid SCHEMBL5224199 | 0.75 | CSNK1E (0.50) | CETPMME | |
| Hydrochloric Acid SCHEMBL5219524 | 0.74 | CSNK1E (0.49) | CETPMME | |
| SCHEMBL5385780 | 0.73 | CSNK1E (0.51) | MME | |
| SCHEMBL4047070 | 0.73 | ALDH1A1 (0.42) | CTSLCTSBALDH1A1ADRB2HTT | |
| Hydrochloric Acid SCHEMBL5225719 | 0.72 | CSNK1E (0.50) | MME | |
| SCHEMBL5391447 | 0.72 | ABCB1 (0.46) | ADRB2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |