Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218306 | 1.00 | USP2 (0.62) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711402 | 0.89 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711279 | 0.89 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7361266 | 0.88 | USP2 (0.60) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711333 | 0.88 | USP2 (0.60) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6965437 | 0.88 | USP2 (0.64) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5324841 | 0.87 | USP2 (0.59) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711222 | 0.87 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711176 | 0.87 | USP2 (0.59) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711344 | 0.87 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280120-A1 | COMPOUND INDUCING ANGIOGENESIS RESPONSE IN ISCHAEMIC TISSUES | Green Cross Therapeutics Private Limited (IN) | 2010-11-04 | — | — | US | disclosed |
| EP-1575900-A4 | N-METHYL AMINO ACIDS | UBIQUITOUS TECHNOLOGIES PTY LT (AU) | 2007-02-21 | — | — | EP | disclosed |
| US-20050245432-A1 | N-methyl amino acids | UBIQUITOUS TECHNOLOGIES PTY. LTD. (AU) | 2005-11-03 | — | — | US | disclosed |
| EP-1575900-A1 | N-METHYL AMINO ACIDS | UBIQUITOUS TECHNOLOGIES PTY LTD (AU) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004007427-A1 | N-METHYL AMINO ACIDS | UBIQUITOUS TECHNOLOGIES PTY LTD (AU) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245432-A1 | N-methyl amino acids | VIP, NPPA, PTMS | USP2 1849/4885PSEN1 565/4885PSEN2 422/4885 |
| US-20100280120-A1 | COMPOUND INDUCING ANGIOGENESIS RESPONSE IN ISCHAEMIC TISSUES | FLT4, TEK, VEGFA | USP2 4602/4885PSEN1 4783/4885PSEN2 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.