Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 17/20 | 0.70 |
| ▸ | CCNE2 | O96020 | 13/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.70 |
| ▸ | CDK2 | P24941 | 13/20 | 0.70 |
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3280934 | 0.99 | GSK3B (0.69) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5223900 | 0.92 | GSK3B (0.73) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL3274990 | 0.91 | GSK3B (0.72) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL5221890 | 0.85 | GSK3B (0.55) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5222268 | 0.85 | GSK3B (0.82) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL3273594 | 0.84 | GSK3B (0.80) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5220911 | 0.83 | GSK3B (0.76) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5223562 | 0.83 | GSK3B (0.82) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5220043 | 0.83 | GSK3B (0.78) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5224389 | 0.82 | GSK3B (0.80) | GSK3BCCNE2CCNE1CDK2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575942-B1 | COMPOUNDS HAVING SELECTIVE INHIBITING EFECT AT GSK3 | ASTRAZENECA AB (SE) | 2007-05-02 | — | — | EP | claimed |