Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3521681 | 0.90 | NPC1 (0.42) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2654689 | 0.89 | KDM5A (0.43) | MAOBMAPTLMNAPARP15PARP10 | |
| SCHEMBL3523312 | 0.83 | MAOB (0.43) | MAOBMAPTTSHRPARP15PARP10 | |
| SCHEMBL2656240 | 0.79 | GCK (0.65) | CSNK2A2CSNK2A1 | |
| SCHEMBL14381041 | 0.76 | GCK (0.45) | MAPTLMNANOX1CSNK2A2CSNK2A1 | |
| SCHEMBL5222914 | 0.76 | NOX1 (0.42) | MAPTTSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2653455 | 0.76 | AR (0.41) | MAPTTSHRARHTTALDH1A1 | |
| SCHEMBL14505835 | 0.75 | MAOB (0.59) | MAOBMAPTLMNAPARP15PARP10 | |
| SCHEMBL10924850 | 0.74 | KDM4E (0.44) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL15609374 | 0.73 | TDP1 (0.50) | MAOBLMNATSHRPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578745-B1 | BENZOFURAN DERIVATivES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES THEREOF | ASTRAZENECA AB (SE) | 2007-11-14 | — | — | EP | disclosed |