Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 9/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218574 | 0.88 | PTGER1 (0.44) | NOX1GCKPOLBKCNH2PTGER1 | |
| SCHEMBL5221067 | 0.86 | GCK (0.51) | NOX1GCKKCNH2HTTSMN1; SMN2 | |
| SCHEMBL5226263 | 0.84 | NOX1 (0.42) | NOX1POLBCYP3A4CYP2C9METAP2 | |
| SCHEMBL2654604 | 0.79 | GCK (0.51) | NOX1GCKKCNH2HTTSMN1; SMN2 | |
| SCHEMBL2653455 | 0.77 | AR (0.41) | GCKTSHRKCNH2HTTMAPT | |
| SCHEMBL5219286 | 0.76 | MAOB (0.42) | NOX1TSHRMEN1KMT2AHTT | |
| SCHEMBL2654537 | 0.74 | KDM4E (0.43) | GCKPOLBTSHRKCNH2SMN1; SMN2 | |
| SCHEMBL5221627 | 0.73 | NOX1 (0.45) | NOX1GCKTSHRKCNH2MEN1 | |
| SCHEMBL5218374 | 0.73 | PTGER1 (0.45) | NOX1PTGER1ACACBHTTSMN1; SMN2 | |
| SCHEMBL2653764 | 0.70 | LMNA (0.53) | POLBMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578745-B1 | BENZOFURAN DERIVATivES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES THEREOF | ASTRAZENECA AB (SE) | 2007-11-14 | — | — | EP | disclosed |