SCHEMBL5219364

SCHEMBL5219364

CC(=O)NC1(C)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.41
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
FFAR3 O14843 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
DPP4 P27487 2/20 0.34
CNR2 P34972 1/20 0.34
CYP3A4 P08684 2/20 0.33
DRD2 P14416 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CA2 P00918 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5260246 1.00 HTT (0.41) HTTALDH1A1SMN1; SMN2FFAR3HDAC3
SCHEMBL14627310 1.00 HTT (0.41) HTTALDH1A1SMN1; SMN2FFAR3HDAC3
SCHEMBL11955648 1.00 HTT (0.41) HTTALDH1A1SMN1; SMN2FFAR3HDAC3
Hydrochloric Acid SCHEMBL20502497 0.98 HTT (0.40) HTTALDH1A1SMN1; SMN2FFAR3HDAC3
SCHEMBL1446029 0.97 HTT (0.38) HTTALDH1A1SMN1; SMN2FFAR3HDAC3
SCHEMBL9613245 0.92
SCHEMBL7991761 0.87
SCHEMBL1694483 0.80 CNR2 (0.37) ALDH1A1SMN1; SMN2FFAR3HDAC3HDAC1
SCHEMBL13204887 0.79 POLB (0.45) HTTALDH1A1FFAR3KMT2APOLB
SCHEMBL21782563 0.78 HDAC3 (0.35) ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661309-A Sodium sulfate wastewater treatment system 昆山美淼环保科技有限公司 2021-04-16 CN claimed
CN-111547915-A Biochemical pretreatment system of phenol ammonia waste water 昆山美淼环保科技有限公司 2020-08-18 CN claimed
CN-111547914-A Method for recovering phenol from semi-coke wastewater 昆山美淼环保科技有限公司 2020-08-18 CN claimed
CN-111547913-A Method for recovering phenol from phenol-containing wastewater 昆山美淼环保科技有限公司 2020-08-18 CN claimed
EP-0318933-A2 Psychotropic acyclic amide derivatives, a process for preparing them and pharmaceutical compositions Bristol-Myers Squibb Company (US) 1989-06-07 EP claimed
WO-2023064361-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS BIOSPLICE THERAPEUTICS, INC. (US) 2023-04-20 WO disclosed
US-20230019032-A1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-01-19 US disclosed
US-11001575-B1 Benzolactam compounds as protein kinase inhibitors OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2021-05-11 US disclosed
CN-112661309-A Sodium sulfate wastewater treatment system 昆山美淼环保科技有限公司 2021-04-16 CN disclosed
CN-111547915-A Biochemical pretreatment system of phenol ammonia waste water 昆山美淼环保科技有限公司 2020-08-18 CN disclosed
CN-111547913-A Method for recovering phenol from phenol-containing wastewater 昆山美淼环保科技有限公司 2020-08-18 CN disclosed
CN-111547914-A Method for recovering phenol from semi-coke wastewater 昆山美淼环保科技有限公司 2020-08-18 CN disclosed
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
EP-1567488-B1 HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE GLAXO GROUP LTD (GB) 2007-02-21 EP disclosed
US-20060025459-A1 Hydroxyethylamine derivatives for the treatment of alzheimer's disease GLAXO GROUP LIMITED (GB) 2006-02-02 US disclosed
CN-1341594-A Substituted pyrrolidone, thiazolidone or oxazolidone as herbicide ZENECA LTD (GB) 2002-03-27 CN disclosed
EP-0636625-B1 Tricyclic diazepines vasopressin and oxytocin antagonists AMERICAN CYANAMID CO (US) 1999-01-27 EP disclosed
CN-1153512-A Substituted pyrrolidones, thiazolidinones or oxazolidinones as herbicides ZENECA LTD (GB) 1997-07-02 CN disclosed
US-3960945-A 4-[-(Alkoxy or polyhaloalkoxy)-benzamido]cyclohexanones STERLING DRUG INC. (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019032-A1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS MAPK1, ALK, MAP3K1 HTT 1689/4885ALDH1A1 1598/4885SMN1; SMN2 2550/4885
US-20060025459-A1 Hydroxyethylamine derivatives for the treatment of alzheimer's disease BACE2, PSEN2, BACE1 HTT 26/4885ALDH1A1 3102/4885SMN1; SMN2 478/4885
US-11001575-B1 Benzolactam compounds as protein kinase inhibitors MAPK1, ALK, MAP3K1 HTT 1760/4885ALDH1A1 1601/4885SMN1; SMN2 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.