SCHEMBL1694483

SCHEMBL1694483

CC1(NC(=O)O)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.37
FFAR3 O14843 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
DPP4 P27487 2/20 0.34
CYP2C19 P33261 1/20 0.33
P2RX7 Q99572 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22310672 0.97 FFAR3 (0.38) CNR2FFAR3HDAC3HDAC1HDAC2
SCHEMBL1694491 0.92
Hydrochloric Acid SCHEMBL28575747 0.90 FFAR3 (0.36) CNR2FFAR3CYP2C19TSHR
SCHEMBL2694749 0.87
SCHEMBL29665210 0.82 CYP19A1 (0.34) CNR2ALDH1A1SMN1; SMN2
SCHEMBL31110317 0.80 CYP19A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL11955648 0.80 HTT (0.41) CNR2FFAR3HDAC3HDAC1HDAC2
SCHEMBL5260246 0.80 HTT (0.41) CNR2FFAR3HDAC3HDAC1HDAC2
SCHEMBL5219364 0.80 HTT (0.41) CNR2FFAR3HDAC3HDAC1HDAC2
SCHEMBL14627310 0.80 HTT (0.41) CNR2FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3715346-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2024-01-03 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-3092220-B1 VITAMIN C PRODRUGS AND USES THEREOF UNIV FLORIDA (US) 2021-01-20 EP claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
EP-2016044-B1 PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS HARVARD COLLEGE (US) 2020-06-10 EP claimed
EP-3209648-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2020-03-11 EP claimed
EP-2550285-B1 TRIOXACARCINS AND USES THEREOF HARVARD COLLEGE (US) 2017-07-19 EP claimed
CN-120129676-A Compounds, compositions, and methods thereof 海湃泰克(北京)生物医药科技有限公司 2025-06-10 CN disclosed
CN-119451683-A Oligonucleotide compositions and methods thereof 艾米利克斯制药公司 2025-02-14 CN disclosed
US-12215100-B2 Anticancer compounds PHARMA MAR, S.A. (ES) 2025-02-04 US disclosed
CN-119325465-A Biphenyl substituted epithelial sodium channel blocking compounds 帕里昂科学公司 2025-01-17 CN disclosed
CN-119101237-A Branched poly (beta-amino esters), method for the production and use thereof 安徽艾迪特生物科技有限公司 2024-12-10 CN disclosed
WO-2010149688-A2 ANTITUMORAL COMPOUNDS PHARMA MAR, S.A. (ES) 2010-12-29 WO disclosed
US-20100292163-A1 Antitumoral Compounds PHARMA MAR, S.A. (ES) 2010-11-18 US disclosed
EP-2231695-A1 ANTITUMORAL COMPOUNDS Pharma Mar S.A. (ES) 2010-09-29 EP disclosed
WO-2009077401-A1 ANTITUMORAL COMPOUNDS PHARMA MAR, S.A. (ES) 2009-06-25 WO disclosed
US-6967196-B1 Sulfonamide compounds and uses thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2005-11-22 US disclosed
US-4260781-A Process for the manufacture of carbamates HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292163-A1 Antitumoral Compounds TP53, XPO1, TOP2B CNR2 4450/4885FFAR3 3455/4885HDAC3 924/4885
US-12215100-B2 Anticancer compounds TP53, MCL1, MYC CNR2 4772/4885FFAR3 4555/4885HDAC3 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.