Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219646 | 1.00 | ADRB3 (0.43) | ADRB3MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL5224496 | 0.94 | ADRB3 (0.42) | ADRB3MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL5224503 | 0.94 | ADRB3 (0.42) | ADRB3MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL5223464 | 0.93 | ADRB3 (0.41) | ADRB3MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL5223472 | 0.93 | ADRB3 (0.41) | ADRB3MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL5221702 | 0.92 | GAA (0.54) | ADRB3MEN1KMT2AANPEPERAP2 | |
| SCHEMBL5221710 | 0.92 | GAA (0.54) | ADRB3MEN1KMT2AANPEPERAP2 | |
| SCHEMBL5219515 | 0.89 | SLC2A1 (0.46) | ADRB3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5219507 | 0.89 | SLC2A1 (0.46) | ADRB3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5218717 | 0.89 | BCHE (0.42) | MEN1HTTKMT2AL3MBTL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |