Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224503 | 1.00 | ADRB3 (0.42) | ADRB3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5219646 | 0.94 | ADRB3 (0.43) | ADRB3NPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL5219638 | 0.94 | ADRB3 (0.43) | ADRB3NPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL5223472 | 0.90 | ADRB3 (0.41) | ADRB3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5223464 | 0.90 | ADRB3 (0.41) | ADRB3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5221702 | 0.89 | GAA (0.54) | ADRB3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5221710 | 0.89 | GAA (0.54) | ADRB3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5223889 | 0.86 | ALDH1A1 (0.38) | ADRB3OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL5223892 | 0.86 | ALDH1A1 (0.38) | ADRB3OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL5217761 | 0.85 | PLAAT3 (0.43) | ADRB3PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |