Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5211533 | 0.99 | AVPR1A (0.55) | AVPR1AGRM2HTR1AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5211525 | 0.99 | AVPR1A (0.55) | AVPR1AGRM2HTR1AKDM4EALDH1A1 | |
| SCHEMBL5212007 | 0.90 | ALDH1A1 (0.48) | AVPR1AHTR1AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5211566 | 0.89 | ALDH1A1 (0.47) | AVPR1AHTR1AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5211577 | 0.89 | ALDH1A1 (0.47) | AVPR1AHTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL5215865 | 0.77 | AVPR1A (0.59) | AVPR1A | |
| SCHEMBL11059996 | 0.76 | KCNH2 (0.67) | HTR1AKDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL5215034 | 0.76 | MAPT (0.64) | AVPR1AKDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL5215652 | 0.74 | AVPR1A (0.55) | AVPR1A | |
| SCHEMBL11062709 | 0.72 | ALDH1A1 (0.52) | KDM4EALDH1A1KCNH2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558598-B1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LTD (GB) | 2007-07-18 | — | — | EP | claimed |