SCHEMBL522004

SCHEMBL522004

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nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5267527 0.83
SCHEMBL9081365 0.82
SCHEMBL1706017 0.71
SCHEMBL1253974 0.70
SCHEMBL4597173 0.70
SCHEMBL2937278 0.70
SCHEMBL2418191 0.70
SCHEMBL521742 0.69 CA12 (0.40) KDM4E
SCHEMBL1245196 0.69 KDM4E (0.30) KDM4E
SCHEMBL1865882 0.69 GLA (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417082-B1 CATALYTIC WITTIG AND MITSUNOBU REACTIONS UNIV TEXAS (US) 2016-03-16 EP disclosed
US-8901365-B2 Catalytic Wittig and Mitsunobu reactions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-12-02 US disclosed
EP-2417082-A2 CATALYTIC WITTIG AND MITSUNOBU REACTIONS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-02-15 EP disclosed
US-20120029211-A1 Catalytic Wittig and Mitsunobu Reactions THE UNIVERSITY OF TEXAS AT ARLINGTON 2012-02-02 US disclosed
WO-2010118042-A2 CATALYTIC WITTIG AND MITSUNOBU REACTIONS BOARD OF REGENTS THE UNIVERSITY OF TEXAS AT ARLINGTON (US) 2010-10-14 WO disclosed