Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.62 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.48 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220162 | 1.00 | DPP4 (0.62) | DPP4DPP8DPP9EBPDHCR7 | |
| Hydrochloric Acid SCHEMBL5223972 | 0.99 | DPP4 (0.61) | DPP4DPP8DPP9EBPDHCR7 | |
| SCHEMBL5567538 | 0.84 | DPP4 (0.76) | DPP4DPP8DPP9 | |
| SCHEMBL5564968 | 0.84 | DPP4 (0.76) | DPP4DPP8DPP9 | |
| SCHEMBL6609010 | 0.81 | EBP (0.54) | EBPDHCR7EPHX2 | |
| SCHEMBL5215962 | 0.81 | DPP4 (0.69) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5510024 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5510013 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5148938 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5510011 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-B1 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-08-22 | — | — | EP | claimed |