Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.54 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220162 | 0.81 | DPP4 (0.62) | EBPDHCR7EPHX2 | |
| SCHEMBL5220325 | 0.81 | DPP4 (0.62) | EBPDHCR7EPHX2 | |
| Hydrochloric Acid SCHEMBL5223972 | 0.81 | DPP4 (0.61) | EBPDHCR7EPHX2 | |
| SCHEMBL22032778 | 0.76 | EBP (0.69) | EBPDHCR7EPHX2KMT2AMEN1 | |
| SCHEMBL17007408 | 0.74 | EBP (0.60) | EBPDHCR7EPHX2ALDH1A1 | |
| SCHEMBL6605625 | 0.73 | NPSR1 (0.51) | MAPK1ALDH1A1MAPT | |
| SCHEMBL22033858 | 0.72 | EPHX2 (0.62) | EBPDHCR7EPHX2ALDH1A1 | |
| SCHEMBL22033224 | 0.71 | EPHX2 (0.62) | EBPDHCR7EPHX2ALDH1A1MAPT | |
| SCHEMBL22032753 | 0.71 | EPHX2 (0.64) | EBPDHCR7EPHX2KMT2AMEN1 | |
| SCHEMBL22033227 | 0.71 | EBP (1.00) | EBPDHCR7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002553-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |