Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 17/20 | 0.63 |
| ▸ | BACE1 | P56817 | 15/20 | 0.63 |
| ▸ | BACE2 | Q9Y5Z0 | 14/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220513 | 1.00 | CTSD (0.63) | CTSDBACE1BACE2 | |
| SCHEMBL5224333 | 0.97 | CTSD (0.63) | CTSDBACE1BACE2 | |
| SCHEMBL5224360 | 0.97 | CTSD (0.63) | CTSDBACE1BACE2 | |
| SCHEMBL5220511 | 0.93 | BACE1 (0.71) | CTSDBACE1BACE2 | |
| SCHEMBL5221428 | 0.90 | CTSD (0.66) | CTSDBACE1BACE2 | |
| SCHEMBL5220167 | 0.90 | BACE1 (0.52) | CTSDBACE1BACE2 | |
| SCHEMBL5220155 | 0.90 | BACE1 (0.52) | CTSDBACE1BACE2 | |
| SCHEMBL5224310 | 0.90 | BACE1 (0.70) | CTSDBACE1BACE2 | |
| SCHEMBL5260965 | 0.88 | CTSD (0.65) | CTSDBACE1BACE2 | |
| SCHEMBL5219119 | 0.87 | BACE1 (0.52) | CTSDBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |