Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145742 | 0.83 | HPGD (0.47) | HTTALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL3151234 | 0.82 | ACP3 (0.50) | ALDH1A1POLBCYP1A2CYP2C19KMT2A | |
| SCHEMBL6241638 | 0.81 | MAPK1 (0.55) | MAPK1HTTALDH1A1RAB9AHPGD | |
| SCHEMBL28594958 | 0.81 | MAPK1 (0.55) | MAPK1HTTALDH1A1RAB9AHPGD | |
| SCHEMBL11184662 | 0.81 | MEN1 (0.55) | ALDH1A1RAB9ALMNACYP1A2CYP2C19 | |
| SCHEMBL1098155 | 0.80 | ALDH1A1 (0.62) | MAPK1HTTALDH1A1PLA2G1BATG4B | |
| SCHEMBL29597658 | 0.79 | ALDH1A1 (0.50) | MAPK1HTTALDH1A1RAB9AHPGD | |
| SCHEMBL1760821 | 0.79 | ALDH1A1 (0.50) | MAPK1HTTALDH1A1RAB9AHPGD | |
| SCHEMBL1760830 | 0.79 | ALDH1A1 (0.50) | MAPK1HTTALDH1A1RAB9AHPGD | |
| SCHEMBL19581784 | 0.79 | MAPK1 (0.68) | MAPK1HTTALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276732-B1 | AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION\ | DOMPE PHA R MA SPA RES & MFG (IT) | 2007-09-26 | — | — | EP | claimed |
| US-7217707-B2 | Amide of R-2-(aminoaryl)-propionic acid for use in the prevention of leucocyte activation | DOMPE S.P.A. (IT) | 2007-05-15 | — | — | US | claimed |