Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.75 |
| ▸ | CCNE2 | O96020 | 14/20 | 0.75 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.75 |
| ▸ | CDK2 | P24941 | 14/20 | 0.75 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3273488 | 0.99 | GSK3B (0.74) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL5219189 | 0.86 | GSK3B (0.58) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL3274547 | 0.86 | GSK3B (0.78) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5219546 | 0.86 | GSK3B (1.00) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL3274706 | 0.85 | GSK3B (0.98) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL5879341 | 0.84 | GSK3B (0.53) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5222268 | 0.84 | GSK3B (0.82) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5223562 | 0.84 | GSK3B (0.82) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| Hydrochloric Acid SCHEMBL3273865 | 0.83 | GSK3B (0.80) | GSK3BCCNE2CCNE1CDK2GSK3A | |
| SCHEMBL5224389 | 0.83 | GSK3B (0.80) | GSK3BCCNE2CCNE1CDK2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575942-B1 | COMPOUNDS HAVING SELECTIVE INHIBITING EFECT AT GSK3 | ASTRAZENECA AB (SE) | 2007-05-02 | — | — | EP | claimed |