Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.57 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | LCAT | P04180 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686737 | 0.89 | USP30 (0.56) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL1990732 | 0.83 | MALT1 (0.59) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL21227887 | 0.83 | CKS1B (0.53) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL25818614 | 0.81 | KDM4E (0.58) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL3065900 | 0.81 | USP30 (0.49) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL16718831 | 0.81 | JAK2 (0.54) | CHRM4PANK3DPP4 | |
| SCHEMBL3282462 | 0.80 | USP30 (0.47) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL13622626 | 0.80 | CHRM4 (0.56) | USP30MALT1HRH3CHRM4PANK3 | |
| SCHEMBL22686015 | 0.80 | POLB (0.55) | USP30MALT1PANK3THRBCCNC | |
| SCHEMBL29655962 | 0.80 | POLB (0.55) | USP30MALT1PANK3THRBCCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |