Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.81 |
| ▸ | ADORA2A | P29274 | 19/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.81 |
| ▸ | ADORA2B | P29275 | 15/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232897 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL10156540 | 0.89 | ADORA3 (0.85) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL11968432 | 0.88 | ADORA3 (0.74) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL2811320 | 0.88 | ADORA3 (0.74) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL3904472 | 0.88 | ADORA3 (0.74) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL10156565 | 0.87 | ADORA3 (0.80) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL10156530 | 0.87 | ADORA3 (0.82) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL10156549 | 0.87 | ADORA3 (0.82) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL3294999 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL10156554 | 0.86 | ADORA3 (0.80) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861412-A1 | ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY | Novartis AG (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097260-A1 | ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2006-09-21 | — | — | WO | disclosed |