Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600428 | 0.92 | ADAM17 (1.00) | ADAM17MMP13 | |
| SCHEMBL6595702 | 0.91 | ADAM17 (0.71) | ADAM17 | |
| SCHEMBL6599222 | 0.87 | ADAM17 (0.72) | ADAM17 | |
| SCHEMBL6598125 | 0.85 | ADAM17 (0.87) | ADAM17MMP13 | |
| SCHEMBL5253094 | 0.85 | ADAM17 (0.73) | ADAM17MMP13 | |
| SCHEMBL5219500 | 0.84 | ADAM17 (0.83) | ADAM17MMP13 | |
| SCHEMBL6597697 | 0.83 | ADAM17 (0.84) | ADAM17MMP13 | |
| SCHEMBL6595325 | 0.83 | ADAM17 (0.74) | ADAM17MMP13 | |
| SCHEMBL6598627 | 0.83 | ADAM17 (0.84) | ADAM17MMP13 | |
| SCHEMBL6596061 | 0.83 | ADAM17 (0.84) | ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558581-A4 | TRIAZOLONE AND TRIAZOLETHIONE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7074810-B2 | Triazolone and triazolethione derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1558581-A2 | TRIAZOLONE AND TRIAZOLETHIONE DERIVATIVES | Bristol-Myers Squibb Company (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20040116491-A1 | Triazolone and triazolethione derivatives as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme | BRISTOL-MYERS SQUIBB COMPANY | 2004-06-17 | — | — | US | disclosed |
| WO-2004032846-A2 | TRIAZOLONE AND TRIAZOLETHIONE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-22 | — | — | WO | disclosed |