Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.71 |
| ▸ | FAP | Q12884 | 9/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5223158 | 0.99 | DPP4 (0.70) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5220422 | 0.86 | DPP4 (0.53) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5216154 | 0.83 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5219230 | 0.83 | DPP4 (0.98) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL6860819 | 0.82 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL6832198 | 0.82 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5987446 | 0.82 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3165078 | 0.82 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL356162 | 0.81 | DPP4 (0.98) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL295498 | 0.81 | DPP4 (0.98) | DPP4FAPDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399420-B1 | PYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-12-05 | — | — | EP | disclosed |
| US-7196201-B2 | Pyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196201-B2 | Pyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196201-B2 | Pyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-20040167341-A1 | Pyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167341-A1 | Pyrrolidines as dipeptidyl peptidase inhibitors | DPP4, DPP3, DPP7 | DPP4 1/4885FAP 15/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.