Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 17/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349998 | 1.00 | VIPR2 (0.43) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7612571 | 0.81 | VIPR2 (0.47) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7612578 | 0.81 | VIPR2 (0.47) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565572 | 0.79 | VIPR2 (0.60) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565577 | 0.79 | VIPR2 (0.60) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565574 | 0.79 | VIPR2 (0.60) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL5394038 | 0.78 | KLK5 (0.51) | VIPR2 | |
| SCHEMBL5394031 | 0.78 | KLK5 (0.51) | VIPR2 | |
| SCHEMBL5379247 | 0.78 | KLK5 (0.51) | VIPR2 | |
| SCHEMBL5379243 | 0.78 | KLK5 (0.51) | VIPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |