Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 17/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565574 | 1.00 | VIPR2 (0.60) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565572 | 1.00 | VIPR2 (0.60) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7300253 | 0.88 | VIPR2 (0.70) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7300250 | 0.88 | VIPR2 (0.70) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565598 | 0.88 | MMP9 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565631 | 0.88 | MMP9 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL9565595 | 0.88 | MMP9 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL6466122 | 0.87 | VIPR2 (0.69) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL15713420 | 0.86 | VIPR2 (0.66) | VIPR2MMP9 | |
| SCHEMBL15714613 | 0.86 | VIPR2 (0.66) | VIPR2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528661-A2 | HIV protease inhibitors with N-terminal polyether substituents | MERCK & CO. INC. (US) | 1993-02-24 | — | — | EP | disclosed |