Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ocrylate SCHEMBL20395024 | 1.00 | TSHR (0.56) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| Enbucrilate SCHEMBL20395020 | 0.94 | TSHR (0.58) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL719001 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL2903638 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL379519 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL35540 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL973728 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL3457991 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| Ocrylate SCHEMBL29891 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 | |
| SCHEMBL15229291 | 0.94 | TSHR (0.62) | TSHRALDH1A1NAAAHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238363-B2 | Modification of medical prostheses | BAYLOR COLLEGE OF MEDICINE (US) | 2007-07-03 | — | — | US | disclosed |
| EP-1737378-A2 | NOVEL MODIFICATION OF MEDICAL PROSTHESES | Baylor College of Medicine (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050271694-A1 | Novel modification of medical prostheses | BAYLOR COLLEGE OF MEDICINE | 2005-12-08 | — | — | US | disclosed |
| WO-2005096990-A2 | NOVEL MODIFICATION OF MEDICAL PROSTHESES | BAYLOR COLLEGE OF MEDICINE (US) | 2005-10-20 | — | — | WO | disclosed |