Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222119 | 0.94 | KMT2A (0.44) | ALDH1A1LMNAL3MBTL1NPSR1KDM4E | |
| SCHEMBL5226884 | 0.87 | MAPK14 (0.50) | KDM4ENPC1RAB9A | |
| SCHEMBL1752937 | 0.85 | CSNK1D (0.47) | ALDH1A1LMNAL3MBTL1NPSR1SMN1; SMN2 | |
| SCHEMBL5227004 | 0.84 | NPC1 (0.62) | ALDH1A1LMNAL3MBTL1NPSR1KDM4E | |
| SCHEMBL5225894 | 0.82 | DYRK1A (0.44) | ALDH1A1LMNAL3MBTL1NPSR1KDM4E | |
| SCHEMBL5224304 | 0.79 | ADORA1 (0.53) | ALDH1A1LMNAL3MBTL1NPSR1KDM4E | |
| SCHEMBL1013453 | 0.79 | AKT1 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL5229288 | 0.79 | NPSR1 (0.42) | ALDH1A1LMNAL3MBTL1NPSR1SMN1; SMN2 | |
| SCHEMBL5223322 | 0.78 | BTK (0.50) | ALDH1A1LMNAL3MBTL1NPSR1KDM4E | |
| SCHEMBL8834226 | 0.78 | POLB (0.43) | ALDH1A1LMNAL3MBTL1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |