Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223261 | 0.89 | GSK3B (0.42) | NPSR1ALDH1A1LMNAATMSMN1; SMN2 | |
| SCHEMBL5222256 | 0.87 | PTGS1 (0.46) | NPSR1ALDH1A1CSNK1DMAPK11MAPK14 | |
| SCHEMBL1752937 | 0.85 | CSNK1D (0.47) | NPSR1ALDH1A1LMNAATMSMN1; SMN2 | |
| SCHEMBL1013453 | 0.79 | AKT1 (0.42) | ALDH1A1CSNK1DMAPK11MAPK14KMT2A | |
| SCHEMBL5221958 | 0.79 | ALDH1A1 (0.51) | NPSR1ALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1597390 | 0.78 | MAPK14 (0.60) | SMN1; SMN2CSNK1DMAPK11MAPK14 | |
| SCHEMBL5225080 | 0.77 | NPSR1 (0.50) | NPSR1ALDH1A1LMNAATMSMN1; SMN2 | |
| SCHEMBL5224594 | 0.76 | ADORA2A (0.41) | NPSR1ALDH1A1LMNAATMSMN1; SMN2 | |
| SCHEMBL1041929 | 0.76 | KIF11 (0.50) | CSNK1DMAPK11MAPK14MEN1KMT2A | |
| SCHEMBL30042717 | 0.76 | KIF11 (0.50) | CSNK1DMAPK11MAPK14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |