Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 4/20 | 0.43 |
| ▸ | LAP3 | P28838 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225738 | 0.88 | CASR (0.46) | CASRLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5219338 | 0.83 | CSNK1E (0.40) | CASRLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5225568 | 0.82 | CASR (0.46) | CASRLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5217674 | 0.82 | CSNK1E (0.49) | CASRLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5396321 | 0.80 | CSNK1E (0.51) | CASRLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4693472 | 0.80 | LAP3 (0.50) | CTSDBACE1BACE2CASRLAP3 | |
| Hydrochloric Acid SCHEMBL5217528 | 0.79 | CSNK1E (0.50) | CASRLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5218444 | 0.79 | CSNK1E (0.47) | BACE1CASRLAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL5222718 | 0.79 | LAP3 (0.49) | CTSDBACE1BACE2CASRLAP3 | |
| SCHEMBL5220211 | 0.79 | BACE1 (0.44) | CTSDBACE1BACE2CASRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |