Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.69 |
| ▸ | CTSD | P07339 | 19/20 | 0.69 |
| ▸ | BACE2 | Q9Y5Z0 | 18/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL5222365 | 0.91 | BACE1 (0.79) | BACE1CTSDBACE2 | |
| SCHEMBL5223127 | 0.91 | BACE1 (0.83) | BACE1CTSDBACE2 | |
| SCHEMBL5222019 | 0.89 | CTSD (0.83) | BACE1CTSDBACE2 | |
| SCHEMBL5218617 | 0.86 | CTSD (0.73) | BACE1CTSDBACE2 | |
| SCHEMBL5222127 | 0.83 | CTSD (0.88) | BACE1CTSDBACE2 | |
| SCHEMBL5222132 | 0.83 | CTSD (0.88) | BACE1CTSDBACE2 | |
| SCHEMBL5221611 | 0.83 | CTSD (0.82) | BACE1CTSDBACE2 | |
| SCHEMBL5220596 | 0.83 | CTSD (0.82) | BACE1CTSDBACE2 | |
| SCHEMBL5222386 | 0.82 | BACE1 (0.71) | BACE1CTSDBACE2 | |
| SCHEMBL5219470 | 0.82 | CTSD (1.00) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |