SCHEMBL5222741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5216955	0.83	ESR1 (0.54)	ESR1ESR2LMNAMAPTMEN1
	SCHEMBL5216967	0.80	CHEK2 (0.46)	ESR1ESR2LMNAMAPTMEN1
	SCHEMBL5216974	0.80	CMKLR1 (0.38)	ESR1BTKCMKLR1
	SCHEMBL5219863	0.79	ESR1 (0.50)	ESR1EGFRLMNAMAPTKMT2A
	SCHEMBL5216693	0.78	ESR1 (0.49)	ESR1EGFRLMNAMAPTKMT2A
	SCHEMBL5215073	0.78	ESR1 (0.49)	ESR1ESR2EGFRLMNAMAPT
	SCHEMBL5217198	0.75	ESR1 (0.59)	ESR1ESR2EGFRLMNAMAPT
	SCHEMBL5218960	0.75	ESR1 (0.46)	ESR1ESR2EGFRLMNAMAPT
	SCHEMBL5214406	0.75	ESR1 (0.46)	ESR1BTKEGFRLMNAMAPT
	SCHEMBL5215880	0.75	ESR1 (0.52)	ESR1BTKESR2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.