Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920408 | 0.83 | CHEK1 (0.36) | LMNAKCNH2CHEK1AURKADAPK3 | |
| Hydrochloric Acid SCHEMBL7208149 | 0.82 | CHEK1 (0.36) | LMNAKCNH2CHEK1AURKADAPK3 | |
| SCHEMBL11709860 | 0.79 | CA12 (0.38) | OPRK1LMNAPDE3AGABRPGABRD | |
| SCHEMBL9704603 | 0.79 | OPRK1 (0.42) | OPRK1LMNAPDE3AGABRPGABRD | |
| SCHEMBL11750297 | 0.78 | MEN1 (0.35) | LMNASLC6A9 | |
| SCHEMBL28226709 | 0.73 | CHEK1 (0.53) | OPRK1LMNAPDE3AGABRPGABRD | |
| Iodide SCHEMBL11461823 | 0.73 | CHEK1 (0.37) | OPRK1LMNAPDE3APDE4DCHEK1 | |
| SCHEMBL8016066 | 0.72 | KDM4E (0.43) | LMNA | |
| SCHEMBL11658080 | 0.71 | ATM (0.44) | OPRK1GABRPGABRDCACNA1FALB | |
| SCHEMBL11519279 | 0.70 | MEN1 (0.46) | OPRK1LMNACACNA1FALBCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953632-B1 | Use of nanoemulsions for determination of the biocompatibility of lipophilic materials in cell culture test and nanoemulsions suitable therefor | MIBELLE AG COSMETICS (CH) | 2007-09-05 | — | — | EP | disclosed |
| US-20050203898-A1 | System and method for the indexing of organic chemical structures mined from text documents | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2005-09-15 | — | — | US | disclosed |
| US-6265180-B1 | STERILE NONTOXIC DISPERSION FOR USE IN TRANSFERRING MATERIALS INTO CELLS | MIBELLE AG COSMETICS (CH) | 2001-07-24 | — | — | US | disclosed |
| EP-0726257-B1 | 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders, and benzopyrylium intermediates for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2001-04-11 | — | — | EP | disclosed |
| EP-0953632-A1 | Use of nanoemulsions for determination of the biocompatibility of lipophilic materials in cell culture test and nanoemulsions suitable therefor | Mibelle AG Cosmetics (CH) | 1999-11-03 | — | — | EP | disclosed |
| EP-0726257-A1 | 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders, and benzopyrylium intermediates for their preparation | EGIS GYOGYSZERGYAR RT. (HU) | 1996-08-14 | — | — | EP | disclosed |