SCHEMBL52228

SCHEMBL52228

Cc1ccccc1/N=N/c1c(O)ccc2ccccc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.74
MAPT P10636 8/20 0.68
L3MBTL1 Q9Y468 6/20 0.68
MAPK1 P28482 4/20 0.68
KDM4E B2RXH2 3/20 0.68
NPC1 O15118 2/20 0.68
KMT2A Q03164 6/20 0.58
TDP1 Q9NUW8 5/20 0.58
MEN1 O00255 5/20 0.58
LMNA P02545 3/20 0.58
HSP90AA1 P07900 3/20 0.58
ALPL P05186 1/20 0.58
ALPI P09923 1/20 0.58
GAA P10253 1/20 0.58
ALPG P10696 1/20 0.58
CASP3 P42574 1/20 0.58
RECQL P46063 1/20 0.58
MMP14 P50281 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30776094 1.00 THRB (0.74) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL29355974 1.00 THRB (0.74) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL2299642 1.00 THRB (0.74) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL29907006 0.94 THRB (0.75) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL26172954 0.94 KMT2A (0.68) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL4751246 0.94 THRB (0.67) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL591066 0.94 THRB (0.75) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL4667562 0.94 THRB (0.75) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL29356567 0.94 THRB (0.75) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL7777944 0.89 THRB (0.64) THRBMAPTL3MBTL1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10150 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110715999-B High-throughput screening method for 200 chemical risk substances in toy 中国检验检疫科学研究院 2021-08-20 CN claimed
CN-110715999-A High-throughput screening method for 200 chemical risk substances in toy 中国检验检疫科学研究院 2020-01-21 CN claimed
CN-108030955-A A kind of preparation method and applications of dentistry implant antibacterial surface coating 北京化工大学 2018-05-15 CN claimed
CN-108036532-A A kind of preparation method of the low temperature resistant spectral selective absorbing coating of solar energy heat collection pipe 山东龙光天旭太阳能有限公司 2018-05-15 CN claimed
CN-108033477-A A kind of magnesium aluminate spinel coated γ ~ Ce2S3Red colorant and preparation method thereof 景德镇陶瓷大学 2018-05-15 CN claimed
CN-108033908-A A kind of synthetic method of the chloro- N`- of 2- (4`- chlordiphenyl -2- bases) niacinamide 西安近代化学研究所 2018-05-15 CN claimed
CN-108033927-A A kind of compound and its preparation method and application 北京宜生堂医药科技研究有限公司 2018-05-15 CN claimed
CN-106731838-B A kind of lithium isotope efficiently separates method 东莞市联洲知识产权运营管理有限公司 2018-05-11 CN claimed
CN-105733393-B The preparation method of the peelable blue glue of environment-friendly type room temperature fast-curing 顺德职业技术学院 2018-05-11 CN claimed
CN-108003779-A A kind of bio-based materials are modified the preparation method of UV solidfication water polyurethane resins 江南大学 2018-05-08 CN claimed
CN-1035175-C Purification of high purity acrylic acid NIPPON CATALYTIC CHEM IND (JP) 1997-06-18 CN claimed
CN-1144540-A Method for sequence comparison of macromolecules by means of a moving meniscus and use PASTEUR INSTITUT (FR) 1997-03-05 CN claimed
CN-1111236-A Process for preparation of insipid p-nitro-aniline HUA RENQING (CN) 1995-11-08 CN claimed
CN-1104202-A Method for extracting ketomusk from leftover bits of ketomusk in production ZHANG JIMEI (CN) 1995-06-28 CN claimed
CN-1104181-A Precipitated barium sulfate production method by using slat mud ZHANG GUANGJUN (CN) 1995-06-28 CN claimed
CN-1097930-A Amistallicide and trichloranthus pesticide JINYAN CHEMICAL PLANT HENGYANG (CN) 1995-02-01 CN claimed
EP-0482593-B1 Polymer scale preventive agent, polymerization vessel for preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1995-01-11 EP claimed
CN-1078458-A Make with extra care to high purity acrylic acid in the vinylformic acid manufacturing NIPPON CATALYTIC CHEM IND (JP) 1993-11-17 CN claimed
WO-1993019143-A1 COLORANT-CONTAINING ELECTRORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1993-09-30 WO claimed
US-4015591-A Cholesteric liquid crystalline phase material-dye composition and venapuncture method employing the composition LIQUID CRYSTAL PRODUCTS, INC. (US) 1977-04-05 US claimed