Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.56 |
| ▸ | GAA | P10253 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222526 | 0.88 | GSK3B (0.60) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL13461463 | 0.86 | KDM4E (0.61) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5219391 | 0.85 | GSK3B (0.62) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5197527 | 0.82 | FFAR3 (0.60) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10802998 | 0.82 | FFAR3 (0.42) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5226455 | 0.81 | ALDH1A1 (0.69) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3329183 | 0.80 | NPSR1 (0.59) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5199144 | 0.80 | ALDH1A1 (0.56) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL15756118 | 0.79 | KDM4E (0.61) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5196967 | 0.78 | KDM4E (0.70) | GSK3BALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116369-A1 | Certain compounds, compositions, and methods | CYTOKINETICS, INC. | 2006-06-01 | — | — | US | claimed |
| EP-1814554-A1 | CERTAIN COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| US-20060116369-A1 | Certain compounds, compositions, and methods | CYTOKINETICS, INC. | 2006-06-01 | — | — | US | disclosed |
| WO-2006047537-A1 | CERTAIN COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116369-A1 | Certain compounds, compositions, and methods | PCNA, MKI67, TP53 | GSK3B 2247/4885ALDH1A1 791/4885KDM4E 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.