⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934693 | 0.77 | HSP90AA1 (0.31) | — | |
| SCHEMBL5233949 | 0.70 | TACR1 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL5223002 | 0.62 | CSF1R (0.33) | — | |
| SCHEMBL3082264 | 0.62 | HSP90AA1 (0.33) | — | |
| SCHEMBL2942017 | 0.61 | CSF1R (0.33) | — | |
| SCHEMBL4242304 | 0.60 | — | — | |
| SCHEMBL4819107 | 0.57 | — | — | |
| Trifluoroacetic Acid SCHEMBL3172735 | 0.56 | KIT (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL3172744 | 0.55 | KIT (0.41) | — | |
| Trifluoroacetic Acid SCHEMBL3082267 | 0.54 | CSF1R (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807077-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047277-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | claimed |