Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233949 | 0.77 | TACR1 (0.30) | — | |
| SCHEMBL3082264 | 0.70 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL3172735 | 0.65 | KIT (0.40) | HSP90AA1HSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL3172744 | 0.64 | KIT (0.41) | — | |
| Trifluoroacetic Acid SCHEMBL3082267 | 0.63 | CSF1R (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL2934694 | 0.62 | TACR1 (0.31) | HSP90AA1HSP90AB1 | |
| SCHEMBL3172739 | 0.61 | CSF1R (0.49) | — | |
| SCHEMBL4819107 | 0.58 | — | — | |
| SCHEMBL25840967 | 0.57 | KDM4E (0.40) | HSP90AA1HSP90AB1 | |
| SCHEMBL3965446 | 0.54 | GPR119 (0.44) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222298-A1 | USE OF CFMS INHIBITOR FOR TREATING OR PREVENTING BONE CANCER AND THE BONE LOSS AND BONE PAIN ASSOCIATED WITH BONE CANCER | Janssen Pharmaceutica N.V. (BE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009058801-A1 | USE OF CFMS INHIBITOR FOR TREATING OR PREVENTING BONE CANCER AND THE BONE LOSS AND BONE PAIN ASSOCIATED WITH BONE CANCER | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |